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Posts Tagged ‘retinitis pigmentosa’

Lab Grown Organoids

For over 50 years, organ transplants has helped people with various diseases get a new lease on life. While retinas can be transplanted, the eye itself can’t be transplanted. That means that persons with retinitis pigmentosa, age-related macular degeneration and certain kinds of eye injuries have to deal with compromised vision or eventually blindness. Of […]

Small Items, Big Impact

What do nanoparticles and small-molecule drugs have in common, other than the fact that they are small? They can both be used as therapeutics for vision. Nanoparticles can be used post-op to prevent the rejection of corneal grafts. Small-molecule drugs can be used for the treatment of age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa. […]

Light and Dark

While it is difficult to do near work like reading, writing or certain crafts like needlepoint, in low light, for the most part our eyes adjust and we can maneuver in the space or at least find the light switch. How does our eyes and brain work so that we can see both in low […]

Detecting & Fixing Eye Diseases

In eye diseases like retinitis pigmentosa, age-related macular degeneration and Leber congenital amaurosis, things are going on in the cellular level that occur before anything is detected by way of a test or observation. It would be great if these changes could be detected sooner and if there was a way to stop the deterioration […]

When the Rods & Cones Need Fixing

The rods and cones in the retina do a lot work when it comes to vision. Rods are sensitive to changes in light and dark, as well as shape in movement. Cones are sensitive to one of three colors, red, green and blue, and can detect fine details. If the rods and cones aren’t working […]

Advances in Bionic Vision

If you are of a certain age, you will remember a television show from the 1970s called “Six Million Dollar Man”. The show was about an Air Force Colonel Steve Austin who is seriously injured when a spaceship he is testing crashes. He then has surgery where he receives bionic legs, a bionic left arm […]

The Genes Have It

Genetic research has revealed many things about eye diseases. Two studies in particular have revealed how gene variants in inherited retinal dystrophies (IRDs), such as retinitis pigmentosa, lead to these diseases and how gene therapy can help preserve vision. Whole-Genome Sequences Researchers at the University of California San Diego School of Medicine and at Shiley […]

Stopping Degeneration in its Tracks Part Two

GARP2 and GARP1 aren’t the only things that can negatively affect vision. Runt-related transcription factor 1 (RUNX1) can lead to too many blood vessels in the eye, also known as neovascularization. This leads to vision loss in persons with diabetic retinopathy and plays a role in age-related macular degeneration. Anti–vascular endothelial growth factor (anti-VEGF) drugs […]

Stopping Degeneration in its Tracks Part One

Retinitis pigmentosa is a group of rare genetic disorders that leads to the loss of retina cells. Symptoms include difficulty seeing at night or in low light conditions and the loss of peripheral vision. Age-related macular degeneration is a disease that blurs the central vision that you need for reading and driving. Both disorders are […]

Immune System & Eye Disease: More than Meets the Eye

Having an immune system is a good thing. It deals with bacteria and viruses, so that either we don’t get sick or if we do, our body fights them off and, for the most part, sickness isn’t fatal. Sometimes our immune system doesn’t work the way we want it to. That can range from an […]